Announcements and Circulars

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 March 2023

(1) GRANT OF OPTIONS (2) PROPOSED GRANT OF OPTIONS (3) GRANT OF AWARDS (4) NON-EXEMPTED CONNECTED TRANSACTIONS - PROPOSED AWARD GRANT TO CONNECTED PERSONS (5) NON-EXEMPT CONNECTED TRANSACTION - PROPOSED PERFORMANCE TARGET AWARD GRANT TO CONNECTED PERSONS (6) UPDATE ON THE PREVIOUS PROPOSED PERFORMANCE TARGET AWARD GRANT TO A CONNECTED PERSON

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS

RESIGNATION OF EXECUTIVE DIRECTOR AND CHIEF OPERATING OFFICER

ANNUAL RESULTS ANNOUNCEMENT FOR THE YEAR ENDED 31 DECEMBER 2022

VOLUNTARY ANNOUNCEMENT BUSINESS UPDATE ON THE APPROVAL OF NEW DRUG APPLICATION IN CHINA FOR XERAVA TM FOR THE TREATMENT OF COMPLICATED INTRA-ABDOMINAL INFECTIONS IN ADULT PATIENTS

DATE OF BOARD MEETING

VOLUNTARY ANNOUNCEMENT

Monthly Return of Equity Issuer on Movements in Securities for the month ended 28 February 2023

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 January 2023

LIST OF DIRECTORS AND THEIR ROLES AND FUNCTIONS

CHANGE OF INDEPENDENT NON-EXECUTIVE DIRECTOR AND CHANGE OF COMPOSITION OF BOARD COMMITTEES

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 December 2022

Next Day Disclosure Return

UPDATE IN RELATION TO DISCLOSEABLE TRANSACTION-(1) COLLABORATION AND LICENSE AGREEMENT; AND (2) SHARE ISSUANCE AGREEMENT IN RESPECT OF THE MANUFACTURE, DEVELOPMENT AND COMMERCIALIZATION OF COVID-19 VACCINES AND CERTAIN LICENSED PRODUCTS

Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 November 2022

TERMS OF REFERENCE OF THE REMUNERATION COMMITTEE

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 October 2022

POLL RESULTS OF THE EXTRAORDINARY GENERAL MEETING HELD ON MONDAY, 31 OCTOBER 2022

Notification Letter with Request Form to Non-registered Holders