Announcements and Circulars

VOLUNTARY ANNOUNCEMENT COLLABORATION AND LICENSE AGREEMENT WITH KEZAR TO DEVELOP AND COMMERCIALIZE ZETOMIPZOMIB IN GREATER CHINA AND OTHER ASIAN MARKETS

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 August 2023

Notification Letter with Request Form to Non-registered Holders

Notification Letter with Change Request Form to Registered Shareholders

INTERIM RESULTS ANNOUNCEMENT FOR THE SIX MONTHS ENDED 30 JUNE 2023

DATE OF BOARD MEETING

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 July 2023

(Revised) Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 June 2023

Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 June 2023

POLL RESULTS OF THE ANNUAL GENERAL MEETING HELD ON THURSDAY, 29 JUNE 2023

Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 May 2023

REVISED FORM OF PROXY FOR THE ANNUAL GENERAL MEETING TO BE HELD ON THURSDAY, 29 JUNE 2023

Notification Letter with Request Form to Non-registered Holders

Notification Letter with Change Request Form to Registered Shareholders

FORM OF PROXY FOR THE ANNUAL GENERAL MEETING TO BE HELD ON THURSDAY, 29 JUNE 2023

NOTICE OF ANNUAL GENERAL MEETING

(1) PROPOSED RE-ELECTION OF DIRECTORS (2) PROPOSED GRANTING OF GENERAL MANDATES TO REPURCHASE SHARES AND TO ISSUE SHARES (3) PROPOSED RE-APPOINTMENT OF RETIRING AUDITOR (4) 2022 PROPOSED OPTION GRANT (5) 2022 PROPOSED AWARD GRANT (6) 2022 PROPOSED PERFORMANCE TARGET AWARD GRANT (7) 2023 PROPOSED OPTION GRANT (8) 2023 PROPOSED AWARD GRANT (9) 2023 PROPOSED PERFORMANCE TARGET AWARD GRANT (10) SUPPLEMENTAL INFORMATION RELATING TO GRANT OF OPTIONS AND AWARDS AND (11) NOTICE OF ANNUAL GENERAL MEETING

Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 April 2023

Notification Letter with Request Form to Non-registered Holders

Notification Letter with Change Request Form to Registered Shareholders